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Detoxification Role of Metabolic Glutathione S-Transferase (GST) Genes in Blood Lead Concentrations of Jamaican Children with and without Autism Spectrum Disorder.
Rahbar MH, Samms-Vaughan M, Kim S, Saroukhani S, Bressler J, Hessabi M, Grove ML, Shakspeare-Pellington S, Loveland KA. Rahbar MH, et al. Genes (Basel). 2022 May 29;13(6):975. doi: 10.3390/genes13060975. Genes (Basel). 2022. PMID: 35741737 Free PMC article.
Glutathione S-transferases (GST) are involved in the detoxification of exogenous chemicals including lead (Pb). ...Using a co-dominant genetic model, ASD cases with the Ile/Val genotype for the GSTP1 Ile105Val polymorphism had lower GM BPbCs than TD controls, after adjusti …
Glutathione S-transferases (GST) are involved in the detoxification of exogenous chemicals including lead (Pb). ...Using a co-dominan …
Interactions between Environmental Factors and Glutathione S-Transferase (GST) Genes with Respect to Detectable Blood Aluminum Concentrations in Jamaican Children.
Rahbar MH, Samms-Vaughan M, Zhao Y, Saroukhani S, Bressler J, Hessabi M, Grove ML, Shakespeare-Pellington S, Loveland KA. Rahbar MH, et al. Genes (Basel). 2022 Oct 20;13(10):1907. doi: 10.3390/genes13101907. Genes (Basel). 2022. PMID: 36292793 Free PMC article.
We investigated additive and interactive associations among environmental factors and children's genotypes for glutathione S-transferase (GST) genes (GSTT1, GSTM1, GSTP1), in relation to having a detectable blood aluminum concentration (BAlC) of >5.0 mug/L, using …
We investigated additive and interactive associations among environmental factors and children's genotypes for glutathione S-t …
Additive and Interactive Associations of Environmental and Sociodemographic Factors with the Genotypes of Three Glutathione S-Transferase Genes in Relation to the Blood Arsenic Concentrations of Children in Jamaica.
Rahbar MH, Samms-Vaughan M, Zhao Y, Saroukhani S, Zaman SF, Bressler J, Hessabi M, Grove ML, Shakspeare-Pellington S, Loveland KA. Rahbar MH, et al. Int J Environ Res Public Health. 2022 Jan 1;19(1):466. doi: 10.3390/ijerph19010466. Int J Environ Res Public Health. 2022. PMID: 35010728 Free PMC article.
Since the soil in Jamaica contains As, dietary intake is considered the main source of As exposure in Jamaicans. In addition, glutathione S-transferase (GST) genes, including GSTT1, GSTP1, and GSTM1, play an important role in the metabolism of xenobiotics including As in h …
Since the soil in Jamaica contains As, dietary intake is considered the main source of As exposure in Jamaicans. In addition, glutathione …
Severity of Child Autistic Symptoms and Parenting Stress in Mothers of Children with Autism Spectrum Disorder in Japan and USA: Cross-Cultural Differences.
Porter N, Loveland KA, Saroukhani S, Posey Y, Morimoto K, Rahbar MH. Porter N, et al. Autism Res Treat. 2022 Jul 12;2022:7089053. doi: 10.1155/2022/7089053. eCollection 2022. Autism Res Treat. 2022. PMID: 35864923 Free PMC article.
There was a nonlinear relationship between the child's autistic symptom severity and parenting stress in both countries. We also found some cultural differences: in the parent domain, the relationships between children's SCQ scores and PSI scores differed significan …
There was a nonlinear relationship between the child's autistic symptom severity and parenting stress in both countries. We also foun …
Additive or Interactive Associations of Food Allergies with Glutathione S-Transferase Genes in Relation to ASD and ASD Severity in Jamaican Children.
Saroukhani S, Samms-Vaughan M, Bressler J, Lee M, Byrd-Williams C, Hessabi M, Grove ML, Shakespeare-Pellington S, Loveland KA, Rahbar MH. Saroukhani S, et al. J Autism Dev Disord. 2024 Feb;54(2):704-724. doi: 10.1007/s10803-022-05813-7. Epub 2022 Nov 27. J Autism Dev Disord. 2024. PMID: 36436147
To investigate additive and interactive associations of food allergies with three glutathione S-transferase (GST) genes in relation to ASD and ASD severity in Jamaican children. ...
To investigate additive and interactive associations of food allergies with three glutathione S-transferase (GST) genes in relation t …
Factors associated with blood mercury concentrations and their interactions with three glutathione S-transferase genes (GSTT1, GSTM1, and GSTP1): an exposure assessment study of typically developing Jamaican children.
Zaman SF, Samms-Vaughan M, Saroukhani S, Bressler J, Hessabi M, Grove ML, Pellington SS, Loveland KA, Rahbar MH. Zaman SF, et al. BMC Pediatr. 2024 Jan 4;24(1):14. doi: 10.1186/s12887-023-04452-w. BMC Pediatr. 2024. PMID: 38178055 Free PMC article.
Mercury is a xenobiotic and known neuro-toxicant that affects children's neurodevelopment. Human glutathione S-transferase (GST) genes, including GSTT1, GSTM1, and GSTP1, affect Hg conjugation and elimination mechanisms. ...We used multivariable general linear model …
Mercury is a xenobiotic and known neuro-toxicant that affects children's neurodevelopment. Human glutathione S-transferase (GS …
Interaction of Blood Manganese Concentrations with GSTT1 in Relation to Autism Spectrum Disorder in Jamaican Children.
Rahbar MH, Samms-Vaughan M, Saroukhani S, Lee M, Zhang J, Bressler J, Hessabi M, Shakespeare-Pellington S, Grove ML, Loveland KA. Rahbar MH, et al. J Autism Dev Disord. 2021 Jun;51(6):1953-1965. doi: 10.1007/s10803-020-04677-z. J Autism Dev Disord. 2021. PMID: 32892263 Free PMC article.
Using data from 266 age- and sex-matched pairs of Jamaican children with autism spectrum disorder (ASD) and typically developing (TD) controls (2-8 years), we investigated whether glutathione S-transferase theta 1 (GSTT1) modifies the association between blood manganese co …
Using data from 266 age- and sex-matched pairs of Jamaican children with autism spectrum disorder (ASD) and typically developing (TD) contro …
A single-center, retrospective analysis to compare measurement of fibrinogen using the TEG6 analyzer to the Clauss measurement in children undergoing heart surgery.
Gautam N, Tran V, Griffin E, Elliott J, Rydalch E, Kerr K, Wilkinson AJ, Zhang X, Saroukhani S. Gautam N, et al. Paediatr Anaesth. 2023 Dec 10. doi: 10.1111/pan.14820. Online ahead of print. Paediatr Anaesth. 2023. PMID: 38071737
Despite its contributions to understanding TEG6s in pediatric cardiac surgery, the study's design and inherent biases warrant cautious application of these findings in clinical settings....
Despite its contributions to understanding TEG6s in pediatric cardiac surgery, the study's design and inherent biases warrant cautiou …
Metabolomic profiles in Jamaican children with and without autism spectrum disorder.
Yazdani A, Samms-Vaughan M, Saroukhani S, Bressler J, Hessabi M, Tahanan A, Grove ML, Gangnus T, Putluri V, Mostafa Kamal AH, Putluri N, Loveland KA, Rahbar MH. Yazdani A, et al. ArXiv [Preprint]. 2024 Mar 11:arXiv:2403.07147v1. ArXiv. 2024. PMID: 38560734 Free PMC article. Preprint.
After quality control and imputation of missing values, we performed univariable and multivariable analysis using normalized metabolites while adjusting for covariates, age, sex, socioeconomic status, and child's parish of birth. RESULTS: Our findings revealed unique metab …
After quality control and imputation of missing values, we performed univariable and multivariable analysis using normalized metabolites whi …
21 results